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Dhifaf Sarhan

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1 week ago

Postdoctoral Scholarship in Tumor Immunology and Immunotherapy Karolinska Institutet in Sweden

Degree Level

Postdoc

Field of study

Immunotherapy

Funding

Scholarship-funded postdoctoral training for one year, with the possibility of extension subject to available funding and KI’s scholarship rules. The scholarship amount is tax free, set for twelve months at a time, and paid out on a six-month basis.

Deadline

Nov 20, 2026

Country flag

Country

Sweden

University

Karolinska Institutet

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Keywords

Immunotherapy
Biology
Single-cell Analysis
Medical Science
Tumor Microenvironment
Immune Regulation
Sex Differences
Tumor Immunology
Myeloid Biology

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About this position

This postdoctoral scholarship is based in the Tumor Immunology and Immunotherapy Group led by Senior Lecturer Dhifaf Sarhan at Karolinska Institutet, within the Division of Pathology at the Department of Laboratory Medicine. The project sits at the intersection of human tumor biology and experimental immunology, with a strong focus on how immune regulation shapes antitumor responses.

The group studies how interactions between innate and adaptive immune cells, together with sex differences, influence the organization and function of the tumor microenvironment. A major aim is to understand why immune cells sometimes control tumors but in other settings become excluded or suppressed, and how these mechanisms can be redirected toward therapy.

You will work on a mechanistic project that connects findings from patient-derived tumor material with experimental systems. The role emphasizes translating observations from single-cell analyses and spatial profiling into experimentally testable hypotheses, then probing candidate pathways through functional assays and perturbation studies in mouse tumor models and human culture systems.

The research environment combines clinical and experimental expertise. The group collaborates closely with clinicians and researchers at Karolinska University Hospital and with national and international partners, giving access to patient material, clinical insight, and complementary analytical approaches. Core facilities support advanced flow cytometry, imaging, single-cell profiling, and spatial profiling.

In this position, you are expected to take a leading role in experimental design, data interpretation, and manuscript preparation. The project offers scope to investigate immune exclusion, innate-adaptive immune interactions, and sex-dependent immune regulation within the context of cancer progression and antitumor immunity.

The appointment is a scholarship-funded postdoctoral affiliation at Karolinska Institutet.

Funding details

Scholarship-funded postdoctoral training for one year, with the possibility of extension subject to available funding and KI’s scholarship rules. The scholarship amount is tax free, set for twelve months at a time, and paid out on a six-month basis.

What's required

A PhD in immunology or a closely related field is required. Applicants must have strong experimental expertise in immunology supported by peer-reviewed original research publications, substantial hands-on experience with primary immune cell isolation and culture, multiparameter flow cytometry and functional immune assays, and the ability to independently design, conduct, analyze and interpret experiments using appropriate controls and statistical methods. Good communication skills, collaboration skills, and fluency in written and spoken English are required. Merits include experience with mouse tumor models, orthotopic gastrointestinal cancer models, genetic or pharmacological perturbations, patient-derived tumor material, tumor-immune co-cultures, organoids or tumoroids, multiplex imaging, microscopy, single-cell or spatial profiling, high-dimensional data analysis using R or Python, and student supervision or interdisciplinary research.

How to apply

Submit the application through the Varbi recruitment system. Include proof of doctoral degree, a complete CV, a publication list highlighting up to three relevant original research articles with your contributions, and a one-page summary of your research and motivation. Apply in English or Swedish by 2026-11-20.

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Professors

Senior Lecturer at Karolinska Institutet

University Name
Country flag

Sweden

Research Interests

Immunology

Cell Biology

Tumor Microenvironment

Cancer Biology

Medical Science