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University of Cambridge

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PhD in Endoplasmic Reticulum Transport and Morphoregulation in Neuron (Patho) Physiology University of Cambridge in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Full funding available

Deadline

Dec 8, 2026

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Country

United Kingdom

University

University of Cambridge

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Keywords

Cell Biology
Computer Science
Neurology
Biology
Electrophysiology
Neuropsychology
Medical Science
Genome Editing
Neurodegenerative Disease
High-resolution Imaging
Endoplasmic Reticulum
Physics

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About this position

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on Endoplasmic Reticulum Transport and Morphoregulation in Neuron (Patho) Physiology.

This project sits at the intersection of neuroscience, neurology, cell biology, and medical science, with additional links to physics and computer science through advanced imaging and analysis. The research investigates how endoplasmic reticulum (ER) network integrity, ER morphology, and luminal transport support neuronal function and how ER-shaping proteins may contribute to neuropathologies such as hereditary spastic paraplegia and dementia-related disease.

Planned work includes editing candidate genes in cells that can differentiate into neurons and glia, then studying the effects on ER structure and function using live-cell microscopy, super-resolution imaging, single-particle tracking, and neuronal activity assays such as calcium imaging. There are also focused projects on modulating candidate ER morphogens, including induced degradation approaches, to explore neuronal health and axonal regeneration.

Funding: This is a competition-funded PhD project for the October 2027/28 academic year. Funding competition deadlines mentioned include Gates US round 1 closing on 2026-10-14 and Cambridge Trust/Gates Cambridge round 2 closing on 2026-12-08. Applicants who miss the funding deadlines will need alternative funding. Funding is not available for Lent or Easter 2027 places.

Eligibility: The advert states the project is open to students worldwide. Applicants should be prepared for experimental lab-based research involving gene editing, microscopy, and neuronal activity analysis.

How to apply: Register your interest via the FindAPhD listing and follow the University of Cambridge application process. Be sure to indicate every funding scheme you are eligible for before the relevant deadlines.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

How to apply

Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.

More information can be found here

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