PhD Opportunities in Medical Science in France

This PhD project explores how systemic inflammation during sepsis can alter brain function through glial activation and changes in monoamine metabolism. The work is centered on a neurobiological mechanism linking neuroinflammation, the aryl hydrocarbon receptor (AhR), and the UDP-glucuronosyltransferase UGT1A6a in astrocytes. The advertised research builds on preliminary evidence that glial cells can glucuronidate morphine, that LPS increases this activity in vitro and in vivo, and that this eff...

This PhD project, STILANTIBIO (“How Do Plant Polyphenolic Stilbenoids Act as Antimicrobial Agents?”), explores how plant-derived stilbenoids act against microbes through a combined approach in chemistry, chemical biology, microbiology, and bioinformatics. The doctoral research is part of a collaborative programme with the Institut de Chimie & Biologie des Membranes et des Nano-objets (CBMN) and the Centre de BioInformatique de Bordeaux (CBiB) . The student will work on the design and synthesis o...

This doctoral project focuses on deep generative models for the joint analysis of biological tissue images and spatial molecular measurements . The student will develop new deep learning methods designed to connect image data with spatially resolved molecular information, with the goal of addressing biological questions in collaboration with partner research teams. The research is based in Auguste Genovesio’s team , which works on image analysis and artificial intelligence at IBENS, ENS-PSL , an...

The doctoral project is part of the interdisciplinary AcrioFarm research on overdoses, within the CNRS PRIME team directed by Marie Jauffret-Roustide . It focuses on the experience of opioids among users, with particular attention to access to care and harm reduction in a context marked by the spread of synthetic opioids and rising overdose rates. The thesis will examine users’ preferences for natural and synthetic opioids, their experiences of treatment and harm reduction services, and the prev...

This PhD project is about inverse problems for biomedical images , with a specific focus on mammography and breast cancer risk assessment . The research aims to improve the analysis of X-ray mammograms by developing denoising methods that preserve the fine structural properties of mammographic textures, especially the self-similarity and fractal characteristics that can reveal patterns linked to cancer risk. The thesis is rooted in the challenge that risk-related parenchymal patterns can be diff...

This PhD project investigates the mechanisms, dynamics, and impact of neuromodulation in the olfactory cortex , with a particular focus on cholinergic and GABAergic projections from the basal forebrain . The student will study how these neuromodulatory signals shape olfactory cortical processing during behavior. The research will rely mainly on fiber photometry and optogenetic stimulation in mice performing olfactory behavioral tasks . The project is designed to connect circuit-level activity wi...

This PhD project investigates how mitochondrial dynamics shape macrophage function and contribute to atherosclerosis. The work focuses on MIRO1, a protein involved in mitochondrial transport and dynamics, and asks how it influences mitochondrial behaviour, macrophage metabolism, and inflammatory function in the context of vascular disease. The successful candidate will join Inserm U1065 in Nice, within a research team studying the interplay between immunity, metabolism, and cardiovascular diseas...

This fully funded PhD opportunity at the French Alternative Energies and Atomic Energy Commission (CEA) focuses on multiphysics simulation, applied mathematics, numerical analysis, and scientific computing. The research is situated within CEA’s nuclear engineering and fuel physics applications, with supervision based at CEA Saclay and CEA Cadarache. The doctoral researcher will develop a generic, scalable, and dynamic algorithm for multiphysics coupling. The goal is to detect the interaction str...

This AFM-Telethon PhD fellowship supports doctoral research in France on neuromuscular diseases and rare genetic disorders. It is offered by the French Muscular Dystrophy Association (AFM), a French charity that funds research into muscle and nerve disorders through its telethon. The fellowship is designed for PhD research carried out in a French laboratory as part of a funded project led by the student’s supervisor or head of laboratory. The advertised research area includes topics such as musc...