Postdoc Opportunities in Cell Biology in Luxembourg

This three-year PhD project will investigate the molecular mechanisms underlying liver dysfunction in childhood POLG-related mitochondrial disease, also known as Alpers-Huttenlocher syndrome. POLG disease is an inherited mitochondrial DNA maintenance disorder caused by pathogenic variants in the POLG gene, leading to mitochondrial DNA depletion. Alpers-Huttenlocher syndrome can affect the central nervous system and liver, with clinical manifestations including epilepsy, hepatic dysfunction and, ...

Upcoming postdoctoral and predoctoral opportunities are being prepared by the Colombi and Leonzino labs in a collaborative project based at IGM-CNR in Pavia and IN-CNR at Humanitas Research Hospital in Rozzano, Italy . The research focuses on organelle communication , especially membrane contact sites between organelles, and how these processes control organelle dynamics and function. The project also investigates how disruption of these mechanisms contributes to neurodegenerative disease , incl...