PhD, Master’s & Postdoc Opportunities in Structural Biology in United Kingdom

Harry Low’s Lab at Imperial College London is recruiting a postdoctoral researcher to investigate the structure and mechanism of bacterial secretion systems. The project will use cryo-electron microscopy ( cryo-EM ) and structural biology approaches to understand how these systems function at the molecular level. The work sits at the intersection of bacterial pathogenesis, membrane remodelling and antibiotic discovery. By characterising secretion machinery and its mechanisms, the project aims to...

The University of Manchester is recruiting a full-time, fixed-term postdoctoral Research Associate to join the Kulathu group in the Division of Molecular and Cellular Function, School of Biological Sciences. The project investigates how different ubiquitin signals direct cellular outcomes, with a focus on polyubiquitin chains and cellular quality control. The researcher will develop a nanobody toolkit to recognise distinct polyubiquitin linkages and enable new experiments in ubiquitin biology. T...

The University of Bristol is accepting applications for a funded PhD investigating how free fatty acids regulate beta-coronavirus infection. Co-supervised by Christiane Berger-Schaffitzel, Andrew Davidson, Harriet Mears and Paul Verkade, the project will examine how free fatty acids influence coronavirus infection, replication and evolution. It builds on the discovery of a conserved fatty acid-binding pocket in the coronavirus spike protein. The research combines structural biology, electron cry...

Funded PhD opportunity in viral DNA mimic proteins at the University of Bristol. Professor Mark Dillingham is seeking an enthusiastic PhD student to investigate how bacterial viruses (phages) produce proteins that masquerade as DNA and sabotage molecular machinery in bacterial hosts. The project will focus on discovering new DNA mimic proteins and understanding their mechanisms, including viral targeting of the bacterial DNA-processing enzyme RecBCD. Research will combine computational structura...

[4-year fully funded Norwich Research Park Biosciences Doctoral Training Partnership PhD studentship including payment of tuition fees, a stipend for living expenses (£21,805 for 2026/27), and a Research Training Support Grant of £5,000 per year.] PhD Studentship at the University of East Anglia, based within the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP), investigating how unusual DNA and RNA structures called G-quadruplexes (G4s) regulate fungal growth and infection...

Research Associate in Chemical Biology at the University of Manchester , based in the Manchester Institute of Biotechnology (MIB) and the Michael Smith Building. This fixed-term post (14 months) is part of a Wellcome Trust-funded project in the Jin group, focused on chemical biology , biochemistry , microbiology , and enzymology . The successful candidate will help study a bacterial pathway called sulfoglycolysis , with hands-on responsibilities including plasmid design and cloning, enzyme produ...

PhD opportunity in Engineering Biology at the University of Bristol , offered in collaboration with Prof Dek Woolfson through the SWBio DTP . The project is titled Engineering co-translational protein assembly using de novo designed proteins (Project ID: 3544). It asks how proteins assemble while being synthesised on the ribosome, building on advances in protein structure prediction such as AlphaFold and focusing on the folding and assembly of de novo designed coiled-coil proteins during transla...

[Fees plus a stipend of £21,805 per annum for 2026/7; funded by EPSRC.] PhD Studentship at the University of Exeter in the Physics department on an ambitious project to build a polarisation-resolved nonlinear microscope with true 3D vectorial control of the focal field. This studentship is aimed at a candidate interested in advanced optical instrumentation, structured light, nonlinear microscopy, and the physics of biological tissue. The project will focus on polarisation-resolved second-harmoni...

University of Oxford is advertising a Postdoctoral Research Associate in Structural Mass Spectrometry within the Department of Biochemistry in Oxford, United Kingdom. The post sits in the Newstead group and the Kavli Institute for Nanoscience , working with Professor Simon Newstead and Dr Jo Parker . The research focuses on the native mass spectrometry study of solute carrier (SLC) transporters , with broader links to structural biology , biophysical chemistry , analytical chemistry , proteomics...